Antonio Piga Selected Research

Deferiprone

1/2022	The safety and acceptability of twice-daily deferiprone for transfusional iron overload: A multicentre, open-label, phase 2 study.
7/2013	Cardiovascular function and treatment in β-thalassemia major: a consensus statement from the American Heart Association.
6/2013	Assessment and management of iron overload in β-thalassaemia major patients during the 21st century: a real-life experience from the Italian WEBTHAL project.
8/2011	Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: results of a phase II pilot trial.
7/2011	Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload.
8/2010	Deferiprone.
11/2008	Current status in iron chelation in hemoglobinopathies.
5/2008	Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders.
9/2006	A prospective randomized controlled trial on the safety and efficacy of alternating deferoxamine and deferiprone in the treatment of iron overload in patients with thalassemia.
5/2006	Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis.

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Antonio Piga Research Topics

Disease

35	Iron Overload 01/2022 - 06/2003
27	beta-Thalassemia (Cooley's Anemia) 12/2021 - 09/2002
21	Thalassemia 01/2020 - 09/2002
8	Anemia 01/2019 - 06/2003
7	Heart Diseases (Heart Disease) 01/2022 - 06/2004
6	Siderosis 01/2016 - 05/2006
5	Sickle Cell Anemia (Hemoglobin S Disease) 01/2019 - 12/2009
5	Heart Failure 01/2019 - 10/2004
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2016 - 05/2006
4	Fibrosis (Cirrhosis) 01/2018 - 09/2002
3	Hemoglobinopathies 01/2020 - 11/2008
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 10/2019 - 02/2008
3	Hemochromatosis (Bronze Diabetes) 10/2019 - 07/2013
3	Infections 12/2017 - 12/2012
3	Exanthema (Rash) 02/2008 - 05/2006
2	Inborn Genetic Diseases (Disease, Hereditary) 12/2021 - 11/2004
2	Hypogonadism (Hypergonadotropic Hypogonadism) 12/2021 - 12/2017
2	Arthralgia (Joint Pain) 01/2020 - 07/2002
2	Pain (Aches) 01/2020 - 12/2017
2	Liver Cirrhosis (Hepatic Cirrhosis) 12/2017 - 05/2015
2	Hepatitis C 05/2015 - 09/2002
2	Nausea 07/2011 - 10/2006
2	Hyperferritinemia 05/2011 - 01/2010
2	Agranulocytosis (Granulocytopenia) 08/2010 - 05/2006
2	Joint Diseases (Joint Disease) 08/2010 - 05/2006
2	Weight Gain 08/2010 - 06/2003
2	Hemosiderosis 04/2008 - 07/2006
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	Lung Diseases (Lung Disease) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Atherosclerosis 12/2021
1	Muscular Diseases (Myopathy) 12/2021
1	Dizziness (Lightheadedness) 01/2020
1	Body Weight (Weight, Body) 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Hyperuricemia 01/2020
1	Cardiac Arrhythmias (Arrythmia) 01/2018
1	Osteonecrosis (Kienbock's Disease) 01/2018
1	Acute Chest Syndrome 01/2018
1	Hyperplasia 12/2017
1	Osteoporosis 12/2017
1	Bone Diseases (Bone Disease) 12/2017
1	Spinal Fractures 12/2017
1	Congenital Abnormalities (Deformity) 12/2017
1	Hypothyroidism 12/2017
1	Neoplasms (Cancer) 08/2017
1	Prostatic Neoplasms (Prostate Cancer) 08/2017
1	Proteinuria 11/2016
1	Nephrocalcinosis 02/2016
1	Kidney Calculi (Kidney Stone) 02/2016
1	Hypercalciuria 02/2016
1	Pyelonephritis 02/2016
1	Pneumococcal Infections 08/2015
1	Pulmonary Arterial Hypertension 01/2015

Drug/Important Bio-Agent (IBA)

43	IronIBA 12/2021 - 09/2002
22	Deferasirox FDA Link 01/2021 - 06/2003
16	DeferiproneIBA 01/2022 - 09/2002
13	Chelating AgentsIBA 01/2021 - 06/2003
12	Deferoxamine (Desferal)FDA LinkGeneric 09/2015 - 10/2004
10	Ferritins (Ferritin)IBA 01/2021 - 01/2004
5	Hemoglobins (Hemoglobin)IBA 01/2019 - 12/2012
4	CreatinineIBA 11/2016 - 05/2006
3	Vitamin D FDA LinkGeneric 01/2018 - 12/2017
3	Pharmaceutical PreparationsIBA 11/2016 - 10/2006
3	Alanine Transaminase (SGPT)IBA 06/2013 - 07/2002
2	luspaterceptIBA 01/2020 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2006
2	InterferonsIBA 12/2017 - 05/2015
2	Amlodipine (Norvasc)FDA LinkGeneric 01/2016 - 09/2013
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2012 - 01/2011
2	melanoidin polymersIBA 01/2012 - 01/2011
2	Isoflurophate (DFP)FDA Link 08/2010 - 01/2005
2	Transferrin (beta 2 Transferrin)IBA 01/2009 - 03/2004
1	Oxygen (Dioxygen)IBA 01/2022
1	TabletsIBA 01/2021
1	Sickle HemoglobinIBA 01/2019
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 01/2018
1	Vitamin D3 24-HydroxylaseIBA 01/2018
1	MineralsIBA 12/2017
1	Growth Hormone (Somatotropin)IBA 12/2017
1	ZincIBA 12/2017
1	Antiviral Agents (Antivirals)IBA 12/2017
1	TeaIBA 08/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2017
1	SolutionsIBA 11/2016
1	ElectrolytesIBA 02/2016
1	SaltsIBA 02/2016
1	CalciumIBA 02/2016
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 08/2015
1	Conjugate VaccinesIBA 08/2015
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 08/2015
1	BilirubinIBA 05/2015

Therapy/Procedure

11	Therapeutics 01/2022 - 09/2002
11	Blood Transfusion (Blood Transfusions) 01/2021 - 06/2003
9	Chelation Therapy (Therapy, Chelation) 12/2021 - 09/2002
3	Splenectomy 01/2019 - 09/2011
1	Precision Medicine 10/2019
1	Liver Transplantation 01/2018
1	Ileostomy 12/2016